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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
31.82
Human Site:
S437
Identified Species:
43.75
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S437
A
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S437
A
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S558
A
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Dog
Lupus familis
XP_543550
1017
111618
S437
A
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S437
T
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Rat
Rattus norvegicus
NP_001129232
1015
111665
S437
T
G
V
V
N
G
E
S
L
E
D
I
R
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
V437
A
P
K
V
A
S
M
V
N
G
E
S
L
E
D
Frog
Xenopus laevis
Q8QFR2
1013
112021
S437
A
S
M
M
N
G
E
S
L
E
D
I
R
K
N
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S437
T
N
V
L
N
G
E
S
L
E
D
I
R
K
N
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
G437
K
L
N
S
V
M
N
G
E
S
L
E
D
I
R
Fruit Fly
Dros. melanogaster
O17468
1047
113397
R434
T
R
T
K
D
G
K
R
R
I
T
P
M
F
I
Honey Bee
Apis mellifera
XP_001122939
838
91355
G283
I
L
Q
K
K
Q
P
G
S
S
K
P
Q
Q
Y
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
P380
Y
Q
I
Y
S
I
R
P
P
R
Y
E
L
T
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
Q409
P
A
Q
L
L
L
E
Q
A
S
A
K
Q
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S437
S
T
A
K
R
R
K
S
Q
V
D
D
R
N
K
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
R285
D
A
P
T
E
V
A
R
F
N
P
R
L
F
E
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
P435
M
G
A
L
M
G
D
P
G
P
A
Q
K
E
T
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
80
80
0
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
33.3
93.3
86.6
0
20
13.3
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
20
0
13.3
P-Site Similarity:
N.A.
20
N.A.
33.3
0
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
12
12
0
6
0
6
0
6
0
12
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
6
0
6
0
0
0
53
6
6
0
12
% D
% Glu:
0
0
0
0
6
0
53
0
6
48
6
12
0
12
6
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
12
0
% F
% Gly:
0
42
0
0
0
59
0
12
6
6
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
6
0
0
6
0
0
0
6
0
48
0
6
6
% I
% Lys:
6
0
6
18
6
0
12
0
0
0
6
6
6
48
6
% K
% Leu:
0
12
0
18
6
6
0
0
48
0
6
0
18
0
0
% L
% Met:
6
0
6
6
6
6
6
0
0
0
0
0
6
0
0
% M
% Asn:
0
6
6
0
48
0
6
0
6
6
0
0
0
6
48
% N
% Pro:
6
6
6
0
0
0
6
12
6
6
6
12
0
0
0
% P
% Gln:
0
6
12
0
0
6
0
6
6
0
0
6
12
6
0
% Q
% Arg:
0
6
0
0
6
6
6
12
6
6
0
6
53
0
6
% R
% Ser:
6
6
0
6
6
6
0
53
6
18
0
6
0
6
0
% S
% Thr:
24
6
6
6
0
0
0
0
0
0
6
0
0
6
6
% T
% Val:
0
0
42
42
6
6
0
6
0
6
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
6
0
0
0
0
0
0
6
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _